It started with Texas A&M's Myles Garrett going No. 1 overall and ended with Mississippi's Chad Kelly going last as "Mr. Irrelevant."
For the 11th straight year, the SEC led all conferences in number of NFL draft picks.
The league had 23 players taken during the final four rounds Saturday to increase its three-day total to 53, 10 more than the Atlantic Coast Conference.
The ACC closed with a flurry, with 32 of its 43 drafted players taken on the last day.
The Pac-12 edged out the Big Ten 36-35 in picks.
The Big 12 had only 14 players drafted, the fewest since the conference formed from the merger of the Southwest Conference and Big Eight in 1996.