One week remains on MLB's schedule. Although keep in mind that any tiebreaker game—a real possibility in both leagues' wild-card races—classifies as a regular-season contest. As a result, any stats accrued count in fantasy leagues.
Without any long-term ramifications, managers should feel no loyalty to anyone. Don't like a decent pitcher's matchup? Dump him for someone scheduled to tussle against a lesser adversary.
Unsure about someone such as Alex Bregman, who has missed a few days but isn't ruled out for the season yet? Don't hold out hope for two games. Go get someone who will play six or seven.