Manchester City striker Sergio Aguero has been dropped for Argentina's World Cup 2018 qualifier against Bolivia on Tuesday.
Sao Paulo's Lucas Pratto has been brought in to replace the suspended Gonzalo Higuain and will play alongside Lionel Messi.
Coach Edgardo Bauza is aiming to take three points from the game in La Paz after beating Chile 1-0 last week.
Higuain was cautioned in Thursday's win and is suspended for the Bolivia match, along with fellow regulars Javier Mascherano, Lucas Biglia and Nicolas Otamendi, all of whom picked up yellow cards.