Left-hander David Price could not protect Boston's early lead, surrendering six runs (five earned) on seven hits while walking three and striking out five over five innings. Shortstop Xander Bogaerts committed two errors, including a poor feed to Dustin Pedroia in the fifth that allowed Simmons to score and gave the Angels a 6-3 lead.
Red Sox manager John Farrell was tossed by home-plate umpire Phil Cuzzi after arguing balls and strikes in the fifth inning.