Trout and Pujols hit back-to-back homers off Dan Straily in the first inning, and C.J. Cron and Jefry Marte cleared the fences in the third. Kole Calhoun led off the fourth inning vs. Alfredo Simon with another homer, as the Angels scored nine unanswered runs following Joey Votto's two-run shot against Matt Shoemaker in the top of the first.
Trout, Cron, Marte and Calhoun each finished a triple shy of hitting for the cycle.
Shoemaker pitched seven innings and gave up two earned runs on seven hits with seven strikeouts to win his third straight start for the first time since 2014.