With the Reds desperate to force an opener, the Belgium forward collected the ball on the left edge of the area before clipping into the far corner beyond Jordan Pickford to spark joyus scenes inside Anfield.
Origi's strike picked up 39 per cent of the total votes cast to finish ahead of Ben Woodburn's maiden first-team goal versus Leeds, which received 22 per cent.
In third spot was Sadio Mane's stooping header against Watford, while Philippe Coutinho's drive in the same game came fourth.
Cameron Brannagan's spectacular strike for the U23s against Huddersfield Town clinched fifth spot.