Anthony Castonzo is out with a knee sprain. The young left tackle has been a rock along the offensive line and hasn’t missed a game since entering the league. The Colts will be shuffling their line once again, but this is the biggest loss they’ve had to face.
Despite early reports of a minor ankle injury, Colts safety Mike Adams is likely to miss his second straight game. Adams is officially listed as doubtful for Sunday’s game despite having the past three weeks off. He originally injured his ankle returning an interceptions against the Broncos.