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5 storylines: NFL's oldest QB vs. NFL's youngest QB

Here are five storylines ahead of the Indianapolis Colts (5-5) hosting the Tampa Bay Buccaneers (5-5) on Sunday at 1 p.m. at Lucas Oil Stadium:

1) Castonzo out:

For the first time in 67 regular season games the Colts will be without their rock on the offensive line, left tackle Anthony Castonzo. He sprained his right MCL in last week’s win in Atlanta, sensing immediately on a play in the fourth quarter, something was wrong. “I got rolled up on from the side, a guy rolled up on my knee,” Castonzo said.