New signing Jeffrey Schlupp could make his Crystal Palace debut but forwards Wilfried Zaha and Bakary Sako are away at the Africa Cup of Nations.
Defender Scott Dann is rested while a hamstring injury has ruled out striker Fraizer Campbell as Sam Allardyce seeks his first win as Palace boss.
League One Bolton are set to name a similar team to the one that held Palace to a goalless draw on 7 January.
Palace striker Keshi Anderson has been recalled from his loan spell at Bolton.
The winners of the tie will entertain Manchester City on 29 January (16:00 GMT).