The Pittsburgh Panthers are 3-1 both straight up and against the spread in their four meetings with Virginia Tech since the teams renewed their rivalry back in 2012. In a big game in the ACC's Coastal Division, Pitt hosts the Hokies on Thursday night at Heinz Field.
Point spread: The Hokies opened as four-point favorites, according to sportsbooks monitored by Odds Shark (line updates and matchup report).
College football pick, via Odds Shark computer: 37.0-28.3, Hokies (College football picks on every game)
Why Virginia Tech can cover the spread
Virginia Tech bounced back from an embarrassing upset at Syracuse two weeks ago to beat Miami last Thursday 37-16.